Human Vascular cell adhesion molecule 1 (VCAM-1) ELISA Kit
SKU: KTE60068
359,00€Price
This Human Vascular cell adhesion molecule 1 (VCAM-1) ELISA Kit employs a two-site sandwich ELISA to quantitate VCAM1.
Background
Product Info
Application Note
Storage Instruction
VCAM-1 (CD106), a member of the immunoglobulin superfamily, is a cell surface protein expressed by activated endothelial cells and certain leukocytes (such as macrophages). VCAM-1 expression is induced by IL-1β, IL-4, TNF-α and IFN-γ. VCAM-1 binds to leukocyte integrins VLA-4 and α4β7. The rat and mouse SVCAM-1 proteins share approximately 76% amino acid similarity. VCAM-1 is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis.