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Human Transforming growth factor β3 (TGF-β3) ELISA Kit

Human Transforming growth factor β3 (TGF-β3) ELISA Kit

SKU: KTE60511
339,00€Price
This Human Transforming growth factor β3 (TGF-β3) ELISA Kit employs a two-site sandwich ELISA to quantitate TGFB3.
TGF-β3 encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. TGF-β3 is involved in embryogenesis and cell differentiation, and may play a role in wound healing. Mutations in TGF-β3 are a cause of aortic aneurysms and dissections, as well as familial arrhythmogenic right ventricular dysplasia 1.
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