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Human Signal transducer and activator of transcription 6 (STAT6) ELISA Kit

Human Signal transducer and activator of transcription 6 (STAT6) ELISA Kit

SKU: KTE60381
339,00€Price
This Human Signal transducer and activator of transcription 6 (STAT6) ELISA Kit employs a two-site sandwich ELISA to quantitate STAT6.
STAT6 is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins.
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