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Human Probable proline dehydrogenase 2 (PRODH2) ELISA Kit

Human Probable proline dehydrogenase 2 (PRODH2) ELISA Kit

SKU: KTE61133
339,00€Price
This Human Probable proline dehydrogenase 2 (PRODH2) ELISA Kit employs a two-site sandwich ELISA to quantitate PRODH2.
Probable proline dehydrogenase 2 encoded by PRODH2 catalyzes the first step in the catabolism of trans-4-hydroxy-L-proline, an amino acid derivative obtained through food intake and collagen turnover. One of the downstream products of this catabolism is glyoxylate, which in people with disorders of glyoxalate metabolism can lead to an increase in oxalate levels and the formation of calcium-oxalate kidney stones. Therefore, PRODH2 may serve as a therapeutic target against primary hyperoxalurias (PH). PRODH2 is similar to proline dehydrogenase (oxidase) 1, a mitochondrial enzyme that catalyzes the first step in proline catabolism.
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