Human Excitatory amino acid transporter 2 (SLC1A2) ELISA Kit
SKU: KTE60619
339,00€Price
This Human Excitatory amino acid transporter 2 (SLC1A2) ELISA Kit employs a two-site sandwich ELISA to quantitate SLC1A2.
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Product Info
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Storage Instruction
SLC1A2 / EAAT2 is a member of a family of the solute carrier family of proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Ceftriaxone, an antibiotic, has been shown to induce/enhance the expression of EAAT2, resulting in reduced glutamate activity. Ceftriaxone has been shown to reduce the development and expression of tolerance to opiates and other drugs of abuse. EAAT2 may possess an important role in modulating drug addiction and tolerance.